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Tag Archives: Sickle cell

Dear Jack, she’s AS, you’re AS and you’re madly in love. Should you marry her? You want me to answer. You’re afraid one or more of your children will have the SS genotype. If she’s AS and you’re AS, there are three probable biological outcomes: AS, SS, AA. Nature will throw a biological dice! You can’t predict how many of your children will take on each of the genotypes. Has to do with inheritance patterns. All the children may wind up SS; and they may all wind up AA; or AS. Or nature can be a mixologist.

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